Fertility options in Mayer-Rokitansky-Küster-Hauser syndrome
نویسندگان
چکیده
Background: The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is the most common cause of uterine aplasia, with a worldwide frequency 1 in 4500 females. Although abundant literature present regarding different available methods for creating neovagina MRKH syndrome, attention dedicated to these women’s reproductive potential remains insufficient. Methods: Online searches were carried out PubMed database during November and December 2020. search included combination various terms (e.g., MRKH, vaginoplasty, uterus transplantation, infertility treatment, gestational surrogacy, etc.). following inclusion criteria used: (1) articles should be written English or French language. (2) article have been published by an official scientific organization. Results: Until few years ago, only option women was legal adoption, now surrogacy (GS) transplantation (UTx) become new fertility options patients. Discussion: GS officially recognized several countries widely practiced. On other hand, UTx, although great recent technical improvements, far from being all secondary its complexity necessary immunologic therapies.
منابع مشابه
Mayer-Rokitansky-Küster-Hauser syndrome: fertility counseling and treatment.
To date, no literature has focused on the counseling of patients with Mayer-Rokitansky-Küster-Hauser syndrome as relates to their unique fertility challenges. This article is presented as a guide to practitioners in the counseling of patients with varying Mayer-Rokitansky-Küster-Hauser phenotypes regarding individual reproductive potential.
متن کاملMayer-Rokitansky-Küster-Hauser (MRKH) syndrome
The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part (2/3) of the vagina in women showing normal development of secondary sexual characteristics and a normal 46, XX karyotype. It affects at least 1 out of 4500 women. MRKH may be isolated (type I) but it is more frequently associated with renal, vertebral, and, to a lesser ext...
متن کاملEndometriosis in a Patient with Mayer-Rokitansky-Küster-Hauser Syndrome
Objective. To report a case of Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) in which there were two nonfunctional rudimentary uteruses with the presence of ovarian endometrioma, corroborating that there are valid alternative theories to the existence of endometriosis, rather than Sampson's theory alone, such as the coelomic metaplasia theory. Design. A case report. Setting. A tertiary referra...
متن کاملClinical and genetic aspects of Mayer–Rokitansky–Küster–Hauser syndrome
The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome [MIM 277000] is characterised by the absence of a uterus and vagina in otherwise phenotypically normal women with karyotype 46,XX. Clinically, the MRKH can be subdivided into two subtypes: an isolated or type I form can be delineated from a type II form, which is characterised by extragenital malformations. The so-called Müllerian hypoplasia, r...
متن کاملGenetics of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, also referred to as Müllerian agenesis, is the second most common cause of primary amenorrhea. It is characterized by congenital absence of the uterus, cervix, and the upper part of the vagina in otherwise phenotypically normal 46,XX females. MRKH syndrome has an incidence of about 1 in 4,500-5,000 newborn females and it is generally divided into ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical and Experimental Obstetrics & Gynecology
سال: 2021
ISSN: ['0390-6663', '2709-0094']
DOI: https://doi.org/10.31083/j.ceog.2021.03.2442